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development, testing, parameterisation and calibration of a.pubmed
a physiologically based pharmacokinetic model for di-(2-propylheptyl) phthalate (dphp) was developed to interpret the biokinetics in humans after single oral doses. the model was parameterized with in vitro and in silico derived parameters and uncertainty and sensitivity analysis was used dur
single ingestion of di-(2-propylheptyl) phthalate (dphp) by male,a tolerable daily intake of dphp of 0.2 mg/kg body weight has been derived from rat data. because toxicokinetic data of dphp in humans were not available, it was the aim of the present work to monitor dphp and selected metabolites in blood and urine of 6 male volunteers over time following ingestion of a single dphp dose (0.7 mg/kg body weight).
plastificante de pvc al mejor precio dphp
di (2-propylheptyl) phthalate (also known as bis (2-propylheptyl) benzene-1,2-dicarboxylate, di (propylheptyl) orthophthalate, or dphp) is an organic compound with the formula c 28 h 46 o 4. it is a phthalate and is the diester of phthalic acid and the 10-carbon branched-chain alcohol 2-propylheptanol. this colorless, viscous liquid is used for.
di-(2-propylheptyl) phthalate (dphp) and its metabolites in blood of,the elimination half-lives of the compounds ranged from 2.3h (dphp) to 8.2h (cx-mphp). the normalized aucs of the metabolites were lower at the high dose of dphp than at the low one
di-(2-propylheptyl) phthalate (dphp) and its.sciencedirect
di-(2-propylheptyl) phthalate (dphp) does not act as a reproductive toxicant or endocrine disruptor in contrast to other phthalates. considering adverse effects of phthalates to be linked to their metabolism, it was the aim of the present study to investigate in the rat the blood burden of dphp and its metabolites as a basis for understanding the toxicological behavior of dphp.
di-(2-propylheptyl) phthalate (dphp) and its metabolites in blood of,di-(2-propylheptyl) phthalate (dphp) does not act as a reproductive toxicant or endocrine disruptor in contrast to other phthalates. considering adverse effects of phthalates to be linked to their metabolism, it was the aim of the present study to investigate in the rat the blood burden of dphp and its metabolites as a basis for understanding the toxicological behavior of dphp.
(pdf) di(2-propylheptyl) phthalate: a new plasticizer.researchgate
however, we observed a striking tenfold increase (p < 0.05) in dphp concentrations (mean from 57 ng/g dw to 550 ng/g dw) in spm samples, although dphp has been under regulatory scrutiny and.
bis(2-propylheptyl)phthalat wikipedia,meso -stereoisomer. bis (2-propylheptyl)phthalat ist eine brennbare, schwer entzündbare, nicht flüchtige, farblose flüssigkeit, die praktisch unlöslich in wasser ist. sie zersetzt sich bei erhitzung. [1] aufgrund der zwei verzweigten c 10 -seitenketten handelt um ein isomer der didecylphthalate (z. b. didp ).
di(2‑propylheptyl) phthalate determination of mono(2‑propyl-6
commission. di(2‑propylheptyl) phthalate determination of mono(2‑propyl‑6‑carboxyhexyl) phthalate, mono(2‑propyl‑ 6‑hydroxyheptyl) phthalate, and mono(2‑propyl‑6‑oxoheptyl) phthalate in urine by gc‑hr‑ms or gc‑ms/ms. biomonitoring method translation of the german version from 2021. mak collect occup health saf.
di-2-propilheptil ftalato (dphp) resumen del mercado y alcance 2020 a,el mercado di-2-propilheptil ftalato (dphp) se ha dividido adecuadamente en segmentos importantes, según el informe. en el informe se proporciona una descripción detallada de la industria con respecto al tamaño del mercado en términos de los aspectos de volumen y remuneración, junto con el escenario actual del mercado.